Reelin and Neuropsychiatric Disorders

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Reelin and Neuropsychiatric Disorders

Proper neuronal migration and laminar formation during corticogenesis is essential for normal brain function. Disruption of these developmental processes is thought to be involved in the pathogenesis of some neuropsychiatric conditions. Especially, Reelin, a glycoprotein mainly secreted by the Cajal-Retzius cells and a subpopulation of GABAergic interneurons, has been shown to play a critical r...

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ژورنال

عنوان ژورنال: Frontiers in Cellular Neuroscience

سال: 2016

ISSN: 1662-5102

DOI: 10.3389/fncel.2016.00229